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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c60fdb815ae7b9855d4f161ef9712b194d2491708dc2fd77749402f86a92f09' 
  AND token = '+R9z5dA8e2arY+w15KTGPBs70qA5FDyulqFBxCkabTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}