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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2922705a59072e7697c999518cb70b3ff48f517d44fc01f2e951fbcd844234e1' 
  AND token = 'ueBACeD4lNjztyTo76R10uTjDAzBryeorG5SFcOi5us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}