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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecb19d6e15016d1640fb039d1ada1c851a07e88338819295bcbbc5b68c036ea5' 
  AND token = '0iEuJzW9upanNYGEO4KGLs/NUycgVG+YlvHtTH4rjhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}