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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6adea1aca8eca92b19608bf2b06952bbc1971a19b6efb8676b3b4929051d070' 
  AND token = 'Tm1IsVkTb7d5qnsbSIElnzc+odvmO3EJ+qD5rkbYwGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}