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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e42681cae73afa0861327da1518bb8223ac04854d78b5be7a0104ec5cc2f7f6' 
  AND token = 'gA5UKh7KlKCSUEr1D4Bvq+QkJkCkq5MUmS9QTEPLo+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}