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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b72d42f15f9d8a6dbb2ae4167f8a2beb838028025da73e104e6c16be28fb87f1' 
  AND token = '5DHJGosBsCMIukEkCm81vmilpeTRUPJfVu/lTZ7ALZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}