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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f180ee2fe12f9b0d78eb61a66d0908ef108d410173abc72ed0c147f9c960cb0' 
  AND token = '1SZPEjT3pQyq6ANKOh5LQgZGk4MQuaPYFKi04mreLhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}