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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ae18693957e200e200acb2b43dc9168a6154643d28b0a85b143f13636012eed' 
  AND token = 'sEVXyfDVgVIZHbwS4hw2ajWG6+KQ2/1BT1Gx/PeUIZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}