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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1fc7dddcc5d79c073b282f17e5de9bb41328a1eff142f763dd55547f0f1158e' 
  AND token = '1qQQUAZ9+8SO8TXPKxyWcrrtgJHfE6LkRxrb8pfs04k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}