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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e320c961aee4a09c26cf6cf68ec2d86067da4cdc43c00993fcf45778c7093a60' 
  AND token = 'fXYiIBxiJXlCf4g3lxcUlozU2s2tmVf9Dv6PukkJzsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}