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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12793a93e968721ef63b24c5244b09dcc64910613962231b6f0946a51e88331b' 
  AND token = '2I5nS+A0XUf1+SkwuHw9j58r1jt4lIayU5eTpmlSHT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}