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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f679abe3062ac12a81edc31059f66ff9cc64ddb3751ecbcfd7872e78c53bf1c' 
  AND token = 'I/JGYinJ7+t5zr5mx5wcIBCXz/OOFsR3uc7V9M74UQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}