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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af05ce62616ea557cfe7b3151adc848a2b79babca6636e7c3820a87750701ac4' 
  AND token = 'Scgp2HRe82i/4+fkRNMcMsAXVRdwzIoCkKrK0PLUCfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}