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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ada5bc3efcc855de89dbbb6da574bd8e186fe3d01ff3248650fb61cd70f1f9b' 
  AND token = 'quXkDPbpRTw9rcA+C/i4Ku8XATUhNnFOHrR0Di+yxe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}