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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd99502880bd49ed235ee95b71c9b5c9450de41cfe8e48837ad969c95507e5e53' 
  AND token = 'LD+X5MIQOPsG2ZbAY7doXKGMmuKQCWo0LysQDulPYUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}