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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '378b2983a96380d09fbce433c688b209ee3f33d9966b1013aa0b7b1e42445d66' 
  AND token = 'zPgAvbZ6A0YjAoMVVZRIh0Tpzby5vQrRHIA9cUcdcms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}