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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '380cbd4dc1ee72ebd2beaea8bb933294904933cd80cba0fb31186f82b280f52b' 
  AND token = 'iRtiAVk3aRo/iNDmrlHc0Cztn0cAYvuA+FNCmkllR2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}