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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28c8aea295a702ba7e00adefa8a456d0b78d6d6b997383e163208938621c3406' 
  AND token = 'RbFlIRjmY3XsR/dnFXskx3gwGMQoQeKAKwgpUAeu8JU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}