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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '450e410615481a6fdc9405c26b7d4c157302ce010c88839cb86198bf46abacd6' 
  AND token = '5NsNM6RA+4QJxpw5+5qt31C7H2OND9FRFml0rB2rqy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}