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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '648cdbae1381c420aabf505d26962e71c7ae5830b9bc16a22ce3bda2067885fa' 
  AND token = 'xgt5s14lczLq0DW/kE7ecd5aKTo7AzsX3xQ/e9cSUG4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}