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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19432b8c2fe728034ed3b9e44ae155af0d0ff1495d7ee3f9641e1e620ec8ba15' 
  AND token = 'aaHNzkUf64I0D9WHqZVVhdM2W7uD/S8NfIdMdrey4gs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}