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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06ab4fe82e68bd0672684df6798a8b7f1db0347a1de3da1805dede7f25f9be64' 
  AND token = 'py/TPYs4o4bO6IvqyzTbQ8s6/Wo0cQq9IoU1RKCF/jU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}