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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '727aea6d53b2b38b933c5ecafaf1c098ffc1ade2154e8ffe7d9e4573fbb364e8' 
  AND token = 'm0TxzOFcCdMHCCM5fq69d2E+/sYJk5bId4zervy+oQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}