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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c00a1caecfdd23b9506660cf79f57d7b4679c0ed247bde94d3840d6c999a3a86' 
  AND token = 'TOtgxcucPySI/AQI2GCmPqe/ypPjNGpbG0NxzM2QsP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}