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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '065b4e7f45c37314dd40c09e55d47df5aab3dd646d2c1b5de0c4e6750699a247' 
  AND token = 'LwuRzYknbBDh2ihZcz1bzgIOecEQMOZxwTwd28NgNMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}