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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '532ee220a3e49880af9bf0c4c2a8789e2569560c56b4b331b8b3b7eb1b145d46' 
  AND token = 'qkKzl9car1iUq6TnZT1I5rLdOx97OER8WUjpBxRQfgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}