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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cbbc8c6703e2d0109057931dc0644c6bcf1ca14e6513c3bf0eef9158f49fe14' 
  AND token = 'dKMPy/JiMEJlltO/53kyZIl8zkNo7trMpgG2s0deIe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}