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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79f489b9d88ad92588ad3e44e240dd7bfb6f512dff1dcd0b8ef74b1a9054389d' 
  AND token = 'PIl9MtO6d3xvG/UJfb3HXbhzeTd6LXNcEPf7RR3bvS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}