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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00e841282a3bcfcdfbe1f70f762a62b5ef34dfdb82da026ec45c7bec4c1ab22b' 
  AND token = 'WDtkp7NUOQJrUiZfsXRZ0bZ3+GauW0Ips2L3upII/zw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}