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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f44eda741f0cb49480a24e28ebff22dfee699369eabadebed1e76bb62578020c' 
  AND token = '4Lg3Xu5tM9Tmv1tst4zi1+cmWDJaJSrkwgTEwIRcEQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}