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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86b24cd61b427a0255be54c1cdadbd073217acf302cb1752f6da486f04c3ace5' 
  AND token = '5W9l9s/0wOR07kTOZK9Lho8yrcowAodgfrrH1m0kCY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}