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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '721d6b9272db7659ba105957d111d929f5c611ff54244f2d97e6b3c532bf6cd9' 
  AND token = 'PNzQtpnEgywY/DsL26dZ9JQjCbAfpb8EcY3cpKayebs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}