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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd4cd1c250121f3ec253c26706d00978d0524e17d1debd1e82681614b191fe19' 
  AND token = 'GQxPLBlcmD5k7ETVwTwqLQ14ZknreHnF4HmupZyjfL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}