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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82cda254158ba331e550e1c23f7a2d68954a1b8a7eae36fc0f8af46517a3c499' 
  AND token = 'Fw8Fn5++2NQDQs+XrTTXlxySGlmkSOn2hI/jmaxEy28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}