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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a420e2c92573d9ff30dfcc288645fff2c98bb37a4bfd6f8dfc7fed915b4edd6' 
  AND token = 'fU0mgVc8UAxu3gKzgxYpBjg9y/TGgBI1oCo7EUHwfmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}