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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2be8322b9338a9fb035a39720faa7cfcadaa0e6aeb74c335854e035dec6eb341' 
  AND token = 'PyrT0q1zsthQ4XlS0HwL7sLtl35gtJy6B1C9GeDFXaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}