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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '452add5c709e745e6713a918dcd03ca1e89ce0194b5e5d706a1d8a0749cec687' 
  AND token = 'nPId/Y2zP+zAexti/oGt39tWeviMR8efcGYkmdzGTKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}