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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9804a82820bfc217908c07ac46d63649a2a6f4ca958d4401678ad3ed7d3ae510' 
  AND token = 'cxMpUiQTmD8XBlifTyLz680mDklQNVAPAihfhVqGabk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}