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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef20cdcc7e645be53d1c22a26304ad86cbc4e9656b9eb09e5a815893c3f95366' 
  AND token = 'wix9O5jGaapnV2l6E5TxgnwSJCUk9ST2JROSS1XFCRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}