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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '163713cd9ea408cc73dfffef19aaec7d7bca6cfdf0ddca3a09047e11af6b5e99' 
  AND token = 'uOmNEcHYsOHBI/KJRawI/qMnhNu6Xs52XpYDuvOZq7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}