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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9bcb7b320814ded08d2cea4fec8d07ca2b5898adc39644bae5d75ce3e8f755c' 
  AND token = 'Yx1BP8saWPYSBM+ohAE3k6tA/Q0MYSw4KvFB8d/beVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}