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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8aa941490f73a106281fa66d86bafa18fd895d687d1c3c2f33b48c393d7606c0' 
  AND token = 'UJeZTVc0F32jOhrjBMtE9fs1eYb9FNrjaWm7jnju0ZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}