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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4203b0b7a9943d25c5c9f20887aa79b47f88af6ed75ce48074615e961ae75cff' 
  AND token = '/IUU0Q7Trb4iBXTQfm1QyIHScl757LvkM6BE8gii9Z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}