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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbaa52b9c06629403badbbba5ad9fb7d7cd1b69e7da65350f12e78ed80ae8921' 
  AND token = 'kQPpm1aDlQwAI8RUMM1pHrJ+l/EycnvjfenGGryEIgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}