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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0153e8c7575f566a7abb581d7e78173ca7de6ce4df91dae1bb5c67730993258c' 
  AND token = 'Yru0lQlbh+pXVWZs2cxrOcOvIWjE+NvQtcVjxa3ZHf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}