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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c746380966c11637489ee3a043e57426f13465d6a4bd919d1b412836be9e62f' 
  AND token = 'U3z71P6ZPpJVC51cjq/Ie9h6kW6ap0TJTRNqDYu1COw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}