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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0c0b67c015d0095e275d618bcbb65eb22989755b200236ee1bc6b6d86eee1ab' 
  AND token = 'sTj8Fm/DLVtJ6XVxq2vtMisZ19PcJl99UfvJKTDK+O0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}