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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6066fc17df25a4139531939ad9e9e9925cd39a06fe7df67f2b7d2231632b446' 
  AND token = 'NdHow1njFtRgo9n2tFiQ2E98M3kVZ6Frl1C+XCH/jP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}