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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f74f07eb256fd619594cce9445a62d08f7c4bfa82e3593a3c7467db532d67721' 
  AND token = 'SQdrhh5yXXulnmsy2zo5Mx5lR/ykOygJ4wUQ7FI3aeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}