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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '424e5de43c0f3af1e69244599c6da5fa50da38cd38e67733823c16a2a1092d04' 
  AND token = 'ioas2KoR7fZXi3RKA8rKVfP8dZgv7WaknHm3x+ArMz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}